Evaluation of the protective effect of agar-hp hard capsule for peptic ulcer in experimental animals

Imbalance between exogenous damaging agents and protective factors in the gastro-duodenum tract can lead to peptic ulcer disease. Herbal medicines could be an effective treatment human gastric ulcers. This study aimed investigate effect of AGAR-HP hard capsules on cysteamine-induced gastric-duodenal ulcers experimental rats. The animals were divided into five groups: Group 1 (control) group 2 (model) treated with distilled water, 3 received esomeprazole at 10 mg/kg, 4 0.074 g/kg, 5 0.221 g/kg. All rats for seven consecutive days. On day 7, peptic-duodenal induced by oral cysteamine 400 mg/kg. number ulcer, per rat, index each recorded. Compared 2, high dose reduced mean under macroscopic microscopic examinations. These parameters also decreased low doses compared control group. showed some